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Stem Cell News: Stem Cell Treatment, Stem Cell Research & Success Stories

Stem cell news about stem cell treatment will soon be pushing other medical news aside. Why?

The possibilities for stem cell treatment for Parkinsons, diabetes, Multiple Sclerosis, MS, heart failure, ALS, etc., according to scientists, are “breathtaking.”

Because stem cells are the foundation of every cell, organ and tissue in the human body, they will eventually be able to replace or repair damaged tissue, thereby reversing brain and spinal cord injuries and diseases such as diabetes, cardiovascular disease, Multiple Sclerosis, Parkinsons, Alzheimers and blood diseases.

• Although stem cells have been associated with cord blood and with the growing embryo in the media, scientists have found and are now using the millions of "miltipotent" stem cells produced by the adult body itself.

Researchers have reported every major organ in our body to have stem cells available to it, and the proper use and movement of these stem cells will result in a cure for just about everything.

For instance, adult bone marrow produces stem cells that circulate in the blood, and scientists have found stem cells in the adult brain as well as in organs such as the pancreas.

• It was Dr. Samuel Weiss, the director of the Hotchkiss Brain Institute, who first discovered the existence of stem cells in the adult brain in 1992, disproving the long-held notion that neural development is fixed.

Researchers are now working on how best to activate and stimulate these stem cells for regeneration and for healing in order to replace damaged tissues and organs without creating any new problems such as tumors or cancers.

• One aspect of stem cell treatment that is being used successfully by a few physical therapists, but not yet by doctors, is the fact that the brain has stem cells that can be easily planted into any other part of the body with no disruption to the body process.

Stimulating Adult Stem Cells for Stem Cell Treatment

The trick for regenerative medicine is to effectively activate the desired cells for repair.

Researchers have identified specific molecules in the brain that are responsible for awakening and putting to sleep brain stem cells, which, when activated, can transform into neurons (nerve cells) and repair damaged brain tissue.

Dr. Dong Feng Chen, at Schepens Eye Research Institute, believes that tapping the brain's dormant, but intrinsic ability to regenerate itself is the best hope for treatment for people suffering from brain-ravaging diseases such as Parkinson's or Alzheimer's disease or traumatic brain or spinal cord injuries.

• Stem Cell Treatment: Stem Cells Can Be Awakened Say Scientists

Stem Cell Treatment for ALS & Multiple Sclerosis

Stem-cell-based therapy is a promising new approach to handling neurodegenerative diseases, especially Multiple Sclerosis and ALS.

One of the most promising cellular sources is bone-marrow-derived mesenchymal stem cells (MSCs) also termed “multipotent stromal” cells. Clinical trials for familial ALS amyotrophic lateral sclerosis and Multiple Sclerosis are in progress testing MSC-based therapies.

Why this approach?

Bone-marrow–derived MSCs are abundant, and they have strong “neuro-trophic” and “immuno-modulatory” properties, and have been shown to be beneficial in several experimental models of neurological diseases, according to Dimitrios Karussis, MD, neurologist-neuroimmunologist and head of the Multiple Sclerosis Center at Hadassah University Hospital, Ein Kerem, in Jerusalem, Israel.

Immune modulating properties are important in the treatment of MS because numerous studies indicate that MS is initiated by an autoimmune attack on the central nervous system. This over-reaction of the immune system needs to be “modulated” or brought back into balance. This immune MODULATING approach will help MS and potentially other autoimmune disorders.

While scientists are refining stem cell treatment procedures, there are nutraceuticals that ‘MODULATE” the immune system which are available NOW, while stem cell treatment holds the best promise for the future.

Ask Us About Nutraceuticals for Modulating the Immune:

Bone-marrow cells for MS and ALS

"The ability to easily obtain MSCs stem cells from the patient, expand them in culture, and reintroduce them as a graft, as well as the lack of risk for malignant transformation, (they are not tumor forming) make these cells excellent candidates for cell therapy," says Dr. Karussis, "It's not science fiction. We have passed from theory and discussion about stem cells to action."

Dr. Karussis and his team are continuing their work with stem-cell therapy for MS and ALS. The next step, he said, is to develop controlled trials using more injections, more patients, and longer follow-up, ideally in a multicenter setting.

Bone-marrow–derived MSCs for MS and ALS are Reviewed in: Stem Cell Therapy For Neurodegenerative Diseases, (Expert Opin Biol Ther. 2009 Oct 13.) where researchers demonstrate the wide variety of mechanisms by which MSCs can influence neurodegenerative processes.

Stem Cell-Stimulating Extract Found

While the spotlight has been on medical procedures, e.g. stem cell injections, infusions and transplants, scientists have also identified natural substances that act as powerful regenerative supplements that can:

1) simulate human stem cell mobilization,

2) to be neuro protective for Parkinsons and Alzheimers, and can help restore function and heal as well as

3) “modulate” and re-balance the immune – for MS and other auto immune diseases.

For instance:

1) Researchers at the University of Alberta in Canada successfully produced an extract that significantly improves the level of adult stem cells circulating in the blood. They used an AFA water extract that contains a novel ligand to trigger the mobilization of stem cells.

They published a clinical trial showing that people taking the extract had an increase of 25% in the stem cells circulating in their blood. (Cardiovasc Revasc Med. 2007 Jul-Sep;8(3):189-202.)

2) Scientists have also developed a Immune Modulating Protein that has been subjected to 26 clinical trials and is neuro protective.

Clinical trials have shown the mechanism by which this protein is able to protect against further damage, and how it helps to restore function for neurological diseases.

It has also been shown to “modulate” the immune, so that it “re-balances” an overactive immune that is “attacking” the nerves, as in MS, or the joins in Rheumatoid Arthritis, and so on for an auto immune disease.

These clinically proven supplements – an AFA extracts and Nutraceutical proteins are available now -- and can be used while waiting for the refinement of costly stem cell transplant procedures for Multiple Sclerosis, ALS and Parkinsons to begin the road to recovery of function and wellbeing.

There are reports for lasting benefits for people with MS, Multiple Sclerosis and Parkinsons using these clinically proven supplements called nutraceuticals.

• You can ask us to send you the RESEARCH and reports of BENEFITS by people who are using these extracts and nutraceutical proteins.

Ask Us About Stem Cell Stimulating Extract & Protective Protein:

Stem Cell Treatment for Parkinsons

Scientists are busy gaining insight into exactly how stem cells work.

For instance, scientist at the Center for Human Genetics at the Flanders Institute of Biotechnolgy are they are studying both “induced pluripotent cells” and “neurogenic cells” in the adult brain.

They are studying “the role of individual ligands and other components of this “signaling system” of embryonic and adult stem/progenitor cells,” in order to contribute to successful cell-based therapy in the future.” (Cytokine Growth Factor Rev. 2009 Nov 3)

Multiple Stem Cell Infusions: one Parkinsons Patient

Monique, with Parkinson’s had Dual Therapies of Stem Cell Infusions in Mexico and in Rotterdam, Holland. She received two Umbilical Cord Cell Intravenous Infusions. Few people with Parkinson’s condition seem to have engaged in two UCB stem cell therapy therapies, especially by two different medical practitioners.

• Her husband George recorded the improvements in his wife e.g. less slurring of her words, although these effects did not last.

• We will be happy to send you George’s detailed report of Monique’s UCB stem cell therapies:

For More About Monique’s Stem Cell Infusions:

Future Breakthroughs in Stem Cell Treatment for Parkinsons

Researchers at the Whitehead Institute in Cambridge, Mass., have converted skin cells from people with Parkinson’s disease into the general type of neuron that the disease destroys. (March 2009 issue of the journal Cell)

The new approach, though it requires further work, would in principle allow the brain cells that are lost in Parkinson’s to be replaced with cells that carried no risk of immune rejection, since they would be the patients’ own.

Dr. Anders Bjorklund, a pioneer in using cell therapy to treat Parkinson’s, called the Whitehead team’s work “an important new step” in the development of the cell reprogramming technology. To generate cells suitable for transplanting into patients, several more steps are required, said Dr. Bjorklund, who works at Lund University in Sweden.

One is to develop a more precise recipe for generating the dopamine-producing neurons. There are several types, and the Whitehead team does not yet know how closely its cells resemble those of the substantia nigra, the brain region affected in Parkinson’s.

Another hurdle for attaining cells ready for transplant is to prove that all the cells are fully mature, since immature cells can produce tumors.

“We are easily talking about a few years” before achieving cells that could be considered for transplant, Dr. Bjorklund said.

Stem Cell Treatment for Heart Failure Repair

Treatment with stem cells with the potential to regenerate the damaged myocardium is a relatively new approach to heart disease.

The results of most studies are promising, but there are still many unanswered questions. Scientists are working with “Mesenchymal stromal cells” which are a promising source of stem cells for this regenerative therapy.

Clinical studies on stem cell therapy for cardiac regeneration have indeed shown significant improvements in:

1) ventricular pump function,

2) ventricular remodelling,

3) myocardial perfusion,

4) exercise potential and clinical symptoms

compared with conventionally treated control groups. (Future Cardiol. 2009 Nov;5(6):605-17.)

Japanese doctors at the Osaka University Graduate School of Medicine have demonstrated that that SM MSCs (mesenchymal stem cells derived from synovial membrane) are a potential new regeneration therapy candidate for heart failure.

• So far they have been able to demonstrate that transplantation improved cardiac performance in experiments in rats. (J Artif Organs. 2009;12(3):187-93. Epub 2009 Sep 19.)

Stem Cell Transplants & Type 1 Diabetes

Stem cells transplanted into young adults with Type 1 diabetes held the disease at bay and freed most patients from insulin shots for an average of 31 months, according to a study by a Brazilian team at the University of Sao Paulo and researchers in the USA.

Of 23 young adults, 20 given the stem cell treatment were able to stop insulin injections, while tests showed that their bodies took over the production of the hormone.

This stem cell treatment technique is the only treatment capable of reversing diabetes mellitus in humans, according to Julio Voltarelli, the senior author of the study published in the Journal of the American Medical Association.

While 20 of the 23 patients were able to stop insulin shots, over time, 8 relapsed, and 3 did not respond at all.

Major complications of the stem cell treatment included pneumonia in 2 patients, low sperm counts in 9 men and endocrine dysfunction in 3, reported the researchers.

They suggest that biological approaches will improve slowly with the procedures becoming more effective with fewer side effects.

Stem Cell Success Stories: Parkinsons, diabetes, MS

We will be happy to post the details of your story of stem cell treatment or a stem cell therapy on this site:

If you have taken stem cell therapy in clinics in Germany, in Holland, Mexico, in China or elsewhere, we would like to hear from you. • If you have had lasting results from any of these therapies, please let us know!

Share Your Stem Cell Treatment Story:

Stem Cell Treatment, Organ Transplants & Regeneration

Doctors in Barcelona, Spain, have successfully reconstructed a windpipe for the lung which cannot be rejected by giving a woman a new windpipe with tissue partly grown from her own stem cells, eliminating the need for anti-rejection drugs.

The recipient, Claudio Castillo, who had tuberculosis for years, is happy not to have her lung removed after it collapsed, and is able to care for her children again, and walk without getting out of breath. It will, however, take 3 years to make sure that the tissues will hold, and not fall apart.

While this is an important advance, said Allan Kirk, of the American Society of Transplantation, constructing an entire organ is still a long way off.

For the future of organ regeneration, keep an eye on researchers at Wake Forest in North Carolina.

There, Dr. Anthony Atala, director of the Institute of Regenerative Medicine, has made a name for himself as a regenerative medicine wizard, having constructed several fully functioning bladders, and is trying his hand at growing everything from livers to breasts -- in animals, so far.

Dr Atala's success includes growing functioning rabbit penises that allow male rabbits to mate, ejaculate and procreate. (Proceedings of the National Academy of Sciences, 2009)

Stem Cell News: Stem Cell Treatment, Stem Cell Research and Stem Cell Success Stories for Parkinsons, Diabetes and Multiple Sclerosis, MS

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