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Heart Disease: Research Shows Better Predictors Than Cholesterol

Heart disease has long been understood as being caused by a handful of risk factors such as high cholesterol, high blood pressure, overweight and smoking. This is changing. Why? Because these risks have not always added up.

• High cholesterol has certainly been over rated as a single indicator.

• Not everyone who has high cholesterol will have a stroke or heart attack. Not everyone who has a stroke or heart attack has high cholesterol.

Why do Half of All Heart Attacks & Strokes in the US Happen To Middle-Aged People With Normal Cholesterol Readings?

"Over the next 10 years, we'll be rewriting the rules for the detection and treatment of heart disease," says Richard Stein of the Weill Cornell School of Medicine in New York. Why?

"You can tell a patient he did great on a conventional test, and a week later he drops dead," says Eric Topol of the Cleveland Clinic, because "There's always been something missing."

Inflammation, as shown by the amount of "C-reactive proteins" in the blood, has been found to be a strong indicator of future heart disease.

Cardiologist Mora Samia, MD, at Brigham ad Women’s Holspital in Boston, checked 34 different “biomarkers” in women who had no sign of heart disease.

The “biomarker” that gave the most clues about future heart disease was peoples’ level of C-reactive proteins, or CRP, with high levels leading to heart problems.

• CRP is an indication of INFLAMMATION.

Even then, other studies are have shown that C-reactive protein can be an unreliable measure of heart attack risk, especially in people with a positive troponin test.

Better Predictors Identified

Doctors have begun to zero in on a new set of risk factors for heart disease:

1) One of these is for the PRESENCE of an enzyme called MPO.

New tests will soon measures the enzyme myeloperoxidase, or MPO, made in white blood cells. The enzyme is produced when arteries are inflamed and have rupture-prone fatty deposits.

The new tests for MPO are experimental and will not become widely available without more testing, says Teri Manolio of the National Heart, Lung and Blood Institute.

2) Another new risk factor is the ABSENCE of, or low levels of an enzyme called glutathione.

Researchers at Gutenberg University in Mainz, Germany, showed for the first time that LOW LEVELS of the enzyme glutathione also suggest a coming heart attack.

American scientists have also identified glutathione levels as a new predictor. They say that LOW glutathione levels lead to heart attacks and strokes:

The New England Journal of Medicine recently published a study saying that the higher your glutathione levels, the less likely you are to have a heart attack or heart disease.

It appears that HIGH glutathione levels are protective against cardiovascular disease. Glutathione Levels and Risk of Heart Disease

The American Heart Association journal Stroke has also reported research saying that "higher levels of plasma glutathione (GSH) are associated with a lower incidence of cardiovascular disease," particularly cerebral small vessel disease. Glutathione

What Can Be Done About Glutathione Levels?

We checked with glutathione expert Dr. Jimmy Gutman for the relevance of glutathione for cardiac health. Dr. Gutman says that glutathione is beginning to be recognized as an indicator of cardiac health, and the good news is, that you can RAISE your glutathione levels naturally, to reduce your risk!

Why is that? He explains that glutathione is something that the body itself makes. And because glutathione is the body’s Master Antioxidant, it stops the oxidation of fats by making glutathione peroxidase, which keeps the fats in a safer state.

1) Not only does raising glutathione lower cholesterol by stimulating an enzyme called cholesterol carboxylate, but also....

2) Glutathione works by stopping the oxidation of fats and thereby keeping them in a safer state! When fats become oxidized they become stickier end up gumming up the arteries, so the presence of glutathione can prevent this from happening.

3) High Blood Pressure: There are new studies of protein isolates that raise glutathione act as ace inhibitors, and that they stimulate angio-pentin converting enzymes for regulating high blood pressure. They also act like aspirin to prevent clotting.

4) Glutathione has also found to be key substance in our body that regulates the immune system as well as inflammation.

But there is a Catch...

Blood tests for glutathione are not yet widely available, but you can raise your glutathione levels for prevention.

However, raising glutathione levels is not just a matter of taking a pill. "That is like eating brains trying to get smart," says Dr. Gutman.

• Glutathione must be made by the body itself, and to overcome a glutathione deficiency, it is best to use a nutraceutical protein that guarantees providing the proper nutritional pre-cursors for the body to make an adequate supply.

• There are neutraceuticals proven to improve glutathione levels that are listed in the US Physician's Desk Reference, the PDR.

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The Immune and Heart Disease

Some scientists and cardiologists also point out that there is an underlying immune reaction that causes plaque to build up in the arteries that eventually leads to a heart attack or a stroke.

They say that the immune system reacts when LDL cholesterol and homocysteine levels are too high in the artery walls, and it tries to remedy the situation by sending out immune cells to gobble up these threats to the arteries. When the immune system is in “overdrive,” there is inflammation, and it is this inflammation that is being identified as the smoking gun at the scene heart disease. Feeding and Balancing the Immune

The Immune System, Inflammation and Your Heart

Cardiologist Richard Fleming has identified at least 12 conditions that set off the destructive inflammatory response that he highlights to be the cause of heart attacks and strokes, or heart disease.

He explains some the anomalies in the heart disease picture. For example,

1) why people with normal cholesterol levels get heart attacks, and

2) why small, and not big plaques cause most heart attacks.

Dr Fleming and other doctors outline how to bring down the risk factors associated with inflammation: STOP Inflammation NOW! * The Inflammation Cure: How To Combat Hidden Factors of Disease * Dr. Sears, The Anti-Inflammation Zone: Reversing the Silent Epidemic That's Destroying Our Health *

Lowering Inflammation Naturally against Heart Disease

You can have your doctor check your levels of CRP, or C-reactive proteins, as an indication of INFLAMMATION and future heart problems.

Fortunately, when USDA researchers instructed 18 men and women to add about 50 pitted cherries to their diet daily for a month, their CRP fell by 25%.

Tart cherries in particular have been found to have amazing anti inflammatory properties, and they therefore help with pain relief. They also help to get a good night's sleep!

Links for Overcoming Risk of Heart Attack and Stroke

Lowering Your Cholesterol Without the Use of Medications Such As Statins

How I Received the Gift of Having Normal Cholesterol Again

Dr. Dean Ornish is the Heart Surgeon who pioneered how to Reverse Heart Disease Without Drugs or Surgery

Health Discoveries for Preventing Heart Disease: a Heart Attack or Stroke


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