Rheumatoid Arthritis: New Discoveries for Reducing Joint Pain and RA Symptoms
Individuals struggling with the pain and symptoms of Rheumatoid Arthritis (RA) will want to know about new medical discoveries that are helping many people to reduce their SYMPTOMS, especially JOINT PAIN! There are recent discoveries for BALANCING rather than BOOSTING the immune system. How does this new knowledge about "balancing the immune" relate to Rheumatoid Arthritis? RA is considered to be an autoimmune disease, where the immune system is "over the top," and attacks the joints, which causes pain and dysfunction.
Why Balance, Not Boost the Immune?
If you have Rheumatoid Arthritis, it is important that you know about the discovery that your immune can be both "under-active" and "over-active" at the same time!In fact, scientists have reported that with RA there are both "over-active" B cells and "under-active" T cells. This means that ... the "over-activity" is "picking on" the joints, causing inflammation and pain. On the other hand, the "under-activity" represents a weakened ability to deal with "antigens," i.e. to "mop up" excess free radicals and "oxidative stress." This also eventually results in tissue damage and increased inflammation and pain!
Beyond Vitamin Supplements to "Food for the Immune"
There is good news, because there is a pile of scientific data that points to a molecule called glutathione as being key to the regulation of the immune system -- both its ups AND its downs!In fact...there are scientists who have demonstrated a clear IMPROVEMENT OF INFLAMMATION after raising glutathione in affected tissues. Not only are researchers world-wide reporting that high levels of glutathione are related to health and longevity, and that low levels are associated with disease and early death... But also that it plays a key role in keeping our immune system in balance. Glutathione has been identified as THE "food for the immune.” Because RA is considered to be an autoimmune disease, these new findings are particularly relevant. Furthermore, this new discovery is noteworthy to people with Rheumatoid Arthritis now, because it has recently become known that glutathione levels are best raised with nutrition and nutraceuticals rather than with pills or drugs. For research links:
Arthritis and GSH, glutathione
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What Doctors say about raising glutathione as a NATURAL solution to chronic illnesses, and “natural vaccine to regulate the immune.”
"Back To Nature" Discovery
It was Dr. Bounous at McGill University in Montreal, who, after two decades of research, "Ended up identifying the remarkable properties of some proteins that turned out to be the same as the three proteins in mothers’ breast milk.”“It was a back-to-nature call,” according to Dr. Bounous. His discovery was -- the secret of nature to provide a cysteine-rich protein as the natural building block, or precursor, to making glutathione. Anyone with Rheumatoid Arthritis can benefit from this discovery by increasing their glutathione levels safely and naturally, with nutraceuticals to reduce inflammation and pain.
The Compelling Story Behind This Discovery
"Food for the Immune" for Rheumatoid Arthritis
Dr. Gutman, MD, FACEP explains the critical role of Glutathione (GSH) in the maintenance of health and wellness with Rheumatoid Arthritis.
"Glutathione is not yet a household word, but it soon will be, now that we know how important this substance is, " says Dr. Gutman.
Dr. Jimmy Gutman is a glutathione expert and former Chief Resident in Emergency Medicine at Emory University in Atlanta, and Undergraduate Director and Residency Training Director of Emergency Medicine at McGill University in Montreal.
His book, "GSH, Glutathione, Your Body's Most Powerful Protector," explains that Rheumatoid arthritis (RA) is a common chronic inflammatory joint disease that progresses with aging.
"Although its exact cause is unknown, several factors have been identified. Strong evidence shows that many of the changes in Rheumatoid Arthritis-affected joints are the consequence of oxidation and free radical damage.
Some researchers have also implicated poor T-cell activity and overactive B-cell activity. Scientists have also demonstrated that T-cell glutathione (GSH) content in rheumatoid joints are significantly lower than in peripheral T-cells of the same patients."
"Glutathione modulation," concludes Dr Gutman, "may play a significant role," pointing out that a team of rheumatologists from Leiden University Medical Center in the Netherlands demonstrated clear improvement of inflammation at a cellular level by raising glutathione in the affected tissues.
What Happens As We Age
The glutathione antioxidant system is the body’s powerhouse that neutralizes free radicals that would otherwise damage the tissues and organs. It therefore slows the effects of aging. John T. Pinto of Sloan Kettering Cancer Center in New York proclaims GSH “The master antioxidant.” Jean Carper in her bestseller Stop Aging Now! highlights the same point: “You must get your levels of glutathione up if you want to keep your youth and live longer. High blood levels of glutathione predict good health as you age and a long life. Low levels predict early disease and death.” Dr. Gustavo Bounous and other researchers at McGill University demonstrated this anti-aging effect using a natural product to elevate glutathione levels. They fed mice a cysteine rich protein and compared their glutathione levels and lifespan to mice on a standard diet. Not only were the tissue glutathione levels found to be higher, the mice fed this nutraceutical protein had an average life span of 27 months (corresponding to a human age of 80 years) as compared to the control diet average of 21 months (human equivalent of 55 years.) This is an astonishing increase of 30%. Further experiments using other proteins such as caseine (another milk protein) neither increased longevity nor raised glutathione levels.
Discovery
Your Best Protection
There is little doubt that cellular oxidative damage contributes to aging and the many diseases that accompany it, including Rheumatoid Arthritis. It has been documented that those who live for one hundred years or more have unusually high levels of glutathione. We also know that oxy-radicals are highly destructive. So, given that glutathione is a powerful antioxidant, a connection between longevity and healthy glutathione levels does not seem unreasonable. It may at least improve our immune defenses and quality of life at a time when many people experience one health problem after another. Although we are not mice, the extension of this rodent’s life span by 30 to 50% suggests that glutathione may reduce the wear and tear of aging on overall health. Quite apart from the process of aging, good health in general is associated with high GSH levels. And glutathione helps the liver deal with the toxic side of many medications used by the elderly. It may also improve the usefulness of exercise, which in turn elevates the glutathione system and contributes to overall better health and well-being. Glutathione can enhance our immune response at a time when it normally begins to decline, ward off age-related diseases, and especially improve T-cell function – a critical element of the immune system. Glutathione is best raised by adding cysteine-rich protein to the diet.
Immunity, Aging & Rheumatoid Arthritis
Aging is characterized by a decline in the immune system, accounting in part for increased incidence of cancer and other diseases, especially the infections common among aging individuals.
R.K. Fidelius and M.F. Tsan from the Veterans Administration Research Service have linked low glutathione levels with this increased susceptibility.
By both raising and depleting glutathione levels they were able to significantly alter immune responsiveness.
As the immune system ages T-cell lymphocytes undergo the most significant changes, leaving us less able to respond to viruses, bacteria and other threats.
**The same T-cell insufficiency has also been identified in certain autoimmune diseases such as Rheumatoid Arthritis (RA) and systemic lupus erythematosus (SLE).**
Separate study groups were able to enhance immune responsiveness in aging laboratory animals using glutathione or glutathione-promoting drugs like OTC (ornithine decarboxylase) or 2ME (2-mercapto-ethanol), and these tests were carried into human studies.
Tufts University researchers Drs. Simin Meydani & Dayang Wu showed that by adding glutathione to the white blood cells of elderly people, immune activity approached the levels of much younger individuals.
The same team went on to do an in vitro study in humans, feeding subjects supplements to raise glutathione levels. These test had equally positive results in immune response.
These leading researchers in aging and immunology conclude that increased oxidative stress and/or lower consumption of antioxidants contribute to the decline of white-blood cell function and weakened immune response in the aged.
Lowering the Cancer Risks of RA Meds
The drugs for Rheumatoid Arthritis that suppress the immune system also make you more vulnerable to infections and cancers.
People taking Remicade (infliximab) or Huniva (adalimumab) stand a greater chance of developing infections as well as a wide range of cancers, according to a recent report in the Journal of the American Medical Association.
Both medications belong to a class of drugs known as anti-TNF agents which inhibit the pain, swelling and joint damage associated with the illness -- but at a cost, according to rheumatologist Eric Matteson at the Mayo Clinic.
All the more reason to enhance the body's own defense system: glutathione, to prevent having to use these meds, or to minimize their risks.
Implications For Rheumatoid Arthritis?
Those with arthritis pain will likely benefit from raised glutathione levels and experience relief from many of their Rheumatoid Arthritis symptoms. Being able to raise glutathione easily, conveniently and safely through nutrition is a breakthrough health discovery for the arthritic pain of Rheumatoid Arthritis.
Recommendations for Supplements for Rheumatoid Arthritis:
Find out more about:
Rheumatoid Arthritis as an Auto Immune Disease
Health Discoveries: Immune Supplements for Joint Pain and Pain of Rheumatoid Arthritis, RA
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