New Discovery for Dramatic Reduction of Symptoms of Multiple Sclerosis!Individuals are using these discoveries in their road to recovery from Multiple Sclerosis symptoms -- regaining energy and function -– with relapsing remitting as well as with progressive MS! A Big Puzzle With Many Pieces,But...Researchers Have Now Found A Major Culprit!Dr. Jimmy Gutman FACEP, has added up new research about a protective molecule called glutathione, GSH, and its relationship to Multiple Sclerosis.
He presents many studies that have compared groups of Multiple Sclerosis patients to healthy individuals. Among other things, researchers have measured levels of reactive metabolites (breakdown products of oxidation) and of PROTECTIVE ENZYMES, ESPECIALLY GLUTATHIONE. A number of recent studies suggest that an important role is played by oxygen-derived free radical formation and/or LACK OF ADEQUATE ANTIOXIDANT DEFENSES. Who Dunnit?An Italian group headed by Vince Calabrese, for instance, drew samples of cerebrospinal fluid (CSF) through spinal taps. CSF analysis is a good indicator of brain metabolism.THEY FOUND THAT GLUTATHIONE-PEROXIDASE LEVELS IN THE CEREBROSPINAL FLUID OF Multiple Sclerosis PATIENTS WERE CONSISTENTLY LOW. Glutathione & Research Links Their conclusion was that in Multiple Sclerosis, the fundamental activity of anti-oxidation is abnormal and that OXIDATIVE STRESS plays a causative role. Another study looking at CSF was performed by the Swedes G. Ronquist and G. Frithz who tested spinal taps from a large number of patients including those with stroke, seizures, brain tumors and Multiple Sclerosis. **THE CEREBROSPINAL FLUID OF Multiple Sclerosis MS PATIENTS WERE FOUND TO BE ALMOST ENTIRELY LACKING IN Glutathione. There is further evidence of the involvement of FREE RADICAL ELEVATION AND GSH DEPLETION IN MS. Helen Langemann in Switzerland measured GSH levels within Multiple Sclerosis MS plaques themselves. Without exception, they were depleted. Researchers led by I. Singh at the University of South Carolina examined the fundamental tissue abnormality in multiple sclerosis. The actual myelin breakdown occurs to a large part because of the release of strong inflammatory chemicals called cytokines. These cytokines generate huge numbers of free radicals. Pre-treating neurological tissues with glutathione-enhancing NAC, protected these tissues from demyelination. Conversely, when glutathione was chemically depleted the demyelination grew worse. Simpler studies have demonstrated DECREASED BLOOD LEVELS of glutathione in Multiple Sclerosis MS patients, and these have been repeated by many Scandinavian, Italian and North American researchers. **THESE LEVELS AS WELL CAN BE INVERSELY CORRELATED WITH THE DEGREE OF SEVERITY OF AN ATTACK. My Miracle With MS! Yes, There Is A Common Thread...It turns out that the myelin sheaths destroyed by Multiple Sclerosis are made of lipids, fatty substances highly sensitive to damage by lipid peroxidation, a particularly aggressive type of oxidation.Our key metabolic defenses are glutathione and SOD (super-oxide dismutase). It has been shown that elevating these natural defense systems reduces the damage of oxidative stress. Investigations looking specifically at the breakdown products of oxidation have revealed significantly higher levels in MS patients. Pradlip Toshniwal and Edwin Zarling from Loyola University in Chicago went one step further in their studies. They were able to show that these levels of oxidative stress corresponded to the severity of the MS att MS An Autoimmune Disease?Some authors including S.M. LeVine from the University of Kansas suggest that the pathological process leading to the demyelination of nerves is possible because the immune system cooperates with a free radical generating system present within the myelin sheaths.This explanation combines the two hypotheses that describe Multiple Sclerosis – that it is an autoimmune disease, and is also caused by oxidative stress. He describes how during a demyelination episode, macrophages (cells of the immune system that are supposed to act protectively) seek out myelin and release powerful chemicals (lipases, proteinases, H202 and others). These biochemicals result in tremendous levels of oxidative stress. Find out more about Such a hypothesis leads us to believe that either blunting the immune response or minimizing oxidative stress could help MS patients. Immunosuppressive drugs that blunt the immune response have had only limited success. This has driven researchers to find ways to improve antioxidant protection, glutathione modulation being one of the most promising areas. auto immune diseases. How To Protect Against Oxidative Stress?There is, fortunately a huge amount of scientific knowledge this substance called glutathione.There is a world-wide accumulation of studies about this small defensive molecule that is made in virtually every cell of our bodies. It turns out that this is the body’s very own protective mechanisms against oxidative stress! DID YOU KNOW ... THAT IN EVERY CELL OF OUR BODY, nature has built in glutathione as a defensive substance to PROTECT us.... free radicals and oxidation as well as from toxins, carcinogens, bacteria and viruses? A Significant Key?The picture that emerges from this research is that glutathione’s role is to protect us against the main villains that are at the root Multiple Sclerosis in the various theories of its cause:1) free radicals and oxidative stress, 2) an over or under-active immune response 3) toxins and pollutants, and 4) mutations in our DNA. THE PROBLEM IS THAT GLUTATHIONE IS RAPIDLY CONSUMED ON A DAILY BASIS THROUGH NORMAL METABOLISM, ILLNESS AND EVEN EXERCISE. Without a good supply of glutathione, you have an inadequate defense system, and this can eventually lead to illness and to neurodegenerative diseases such as Multiple Sclerosis. Why Have We Not Heard More About This?Because it has not been medically known how to stimulate the body’s own production of glutathione safely and effectively without drugs, so as to promote and restore health.You cannot just take a glutathione pill to raise it! While anti-oxidants like vitamin C and E have become household words, it has not yet become common knowledge that our bodies already have anti-oxidant protection built in! Indeed, vitamins such as C and E cannot be effective without adequate amounts of glutathione. This was not known, until Dr. Gustavo Bounous, at McGill University in Montreal, discovered that when provided with the nutritional precursors for making glutathione, the body has the needed tools to fight off most threats, naturally. His discovery of raising glutathione through nutrition rather than through pharmaceuticals or pills, is considered by some doctors and researchers to be the biggest medical discovery since penicillin. Dr. Bounous' Discovery Because boosting our glutathione levels on a sustained basis had remained somewhat of a mystery, in that it is not simply a matter of eating it in your food, or taking it in a PILL. Why? Because although it is contained in food, it is destroyed by the digestion. Even when supplied intravenously, glutathione has not been found to be effective, as it deteriorates before it gets to where it is needed. It needs to be made by the cell itself, from 3 amino acids, glycine, glutamate and cysteine, and cysteine turns out to be the most important, but most difficult to get. Recommendations for Nutritonal Supplements:Glutathione's Role In Multiple Sclerosis MSCertain findings have been demonstrated consistently in MS patients:The breakdown products of oxidative stress are present in large numbers, and the level of free radical formation corresponds to the severity of the MS attack. Furthermore, glutathione activity is clearly impaired in this disease. Also, individual tissues suffer less free radical damage when antioxidants and glutathione therapy are used. Although this is not a cure, many authors have suggested that reduced oxidative damage would help MS patients, and suggest in particular the helpful role of elevated glutathione levels. Certainly, many people have improved their LEVEL OF ENERGY and dramatically REDUCED their MS symptoms! For FREE E-BookWhat Dr Code and Dr. Gutman Say About Glutathione GSH for Multiple Sclerosis More Pieces for Solving The MS Puzzle!There’s more! The myelin sheaths destroyed by MS are made of lipids, fatty substances highly sensitive to damage by lipid peroxidation, a particularly aggressive type of oxidation. The brain also is composed of about 60% fatty substances!!This makes it crucial to protect the brain and myelin sheaths by adding essential fatty acids to your diet! Research also suggests that low selenium levels are connected to the development of MS. The trace mineral selenium is an essential part of the glutathione peroxidase enzyme and low selenium levels certainly decrease glutathione’s effectiveness. Vitamin D, the sunshine vitamin is now considered to play a role in regulating the immune system. Certainly, the incidence of Multiple Sclerosis increases the further you are from the equator. And indeed, researchers at the University of Toronto have found evidence that vitamin D may be a natural inhibitor of MS!! They recommend supplementing with doses much higher than the normal guidelines. Multiple Sclerosis Linked To Vitamin D DeficiencyThe lack of natural vitamin D from the sun correlates to the geographic distribution of MS. The rate of MS increases the further people live from the equator, but in some Scandinavian countries there appears to be a lower rate of MS among people who eat a lot of fish, a rich source of dietary vitamin D.Researchers say that inheriting genetic risk factors for Multiple Sclerosis is not sufficient to cause this demyelinating disease of the central nervous system; exposure to environmental risk factors is also required. At the University of Wisconsin, researchers have used a form of vitamin D to see if it can inhibit the development of the animal model of MS in mice. Those treated with the hormone 1,25-(oh)2d3 did not develop the disease while those on placebo became ill. Vitamin D may be a natural inhibitor of MS, with evidence coming from experiments with experimental autoimmune encephalomyelitis (eae), a model of MS. Is Vitamin D the Most Overlooked Vitamin? How Much Sunshine Or Vitamin D Do I Need for Multiple Sclerosis? New Scientific Bombshell: Vitamin D Prevents Cancer Health Discoveries for Multiple Sclerosis Cure for Energy, Pain Relief with Nutrition and Dietary Supplements
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